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Pantethine has been shown to help with high cholesterol and high triglycerides.

Pantethine is an excellent choice when it comes to reduction of triglyceride in the body. A daily dose of 900mg has been shown to reduce triglyceride by up to 32% as well as a 19% drop in total cholesterol and a 21% drop in LDL ( the “bad” cholesterol) cholesterol . At the same time, HDL (the “good” cholesterol) rose by 23%. Pantethine also protects the heart and arteries and acts synergistically with vitamin E against cholesterol build up.

Pantethine’s role in optimum heart health cannot be under-estimated. By generating more Co-enzyme A, the heart muscle’s metabolic rate is enhanced, thereby increasing the heart contractile forces. With a stronger contraction, a longer relaxation phase is possible, resulting in the slowing of heart rate. In addition, pantethine also helps to increase the production of omega-3 fatty acid in the body ( EPA, DHA, and other essential oils). Omega-3 fatty acids also have powerful anti-inflammatory effects and reduces the clot promoting fats in cell membranes. Most spectacularly, there are no side effects. – Dr. Lam

Here’s what Chris Kresser has to say about it:

Human studies have shown significant improvement in lipid profiles with pantethine. It has been shown to reduce total and LDL cholesterol and triglycerices and increase HDL cholesterol without any adverse effects.

Pantethine Works by increasing the bioavailability of coenzyme A, which in turn reduces synthesis of fatty acids by 50 percent and cholesterol by 80 percent. 77 It also enhances the removal of arterial cholesterol and reduces plaque formation, endothelial dysfunction, thickening of the arteries 78 and the oxidation of LDL particles.

– Personal Paleo Code, Chris Kresser