{"id":189,"date":"2015-08-26T17:56:39","date_gmt":"2015-08-26T17:56:39","guid":{"rendered":"http:\/\/www.surepaleo.com\/?p=189"},"modified":"2015-08-26T19:02:45","modified_gmt":"2015-08-26T19:02:45","slug":"vitamin-b5-pantethine-pantothenic-acid","status":"publish","type":"post","link":"http:\/\/www.surepaleo.com\/vitamin-b5-pantethine-pantothenic-acid\/","title":{"rendered":"Vitamin B5, Pantethine, Pantothenic Acid"},"content":{"rendered":"
As I collect more information regarding Vitamin B5, it’s different forms and their effects I will post it here.<\/p>\n
It’s the ‘active form’ of Vitamin B5, so it doesn’t need to be converted in your body like Pantothenic acid does.<\/p>\n
“Pantethine, the active form of pantothenic acid (B5), is one of the most important nutrients for adrenal function<\/a>. It is converted into an enzyme called co-enzyme A. Coenzyme A is required to produce adrenal hormones like cortisol and aldosterone, which support healthy adrenal function. The suggested dose of pantethine is 450 mg twice a day with food.” – From Chris Kresser’s Personal Paleo Code<\/p>\n Co-enzyme A is ultimately converted to Acetyl Co-Enzyme A which has several functions in the body. It is produced by the krebs cycle and is part of the citric acid cycle. Therefore, it plays an important part in metabolism.<\/p>\n Anyway, the important thing here is that CoA and cholesterol are used to produce pregnenolone which is the up-stream hormone that is converted into progesterone, then progesterone is converted into either aldosterone or cortisol.<\/p>\n Taking more pregnenolone is often a treatment path for adrenal dysfunction<\/a>, but taking high-ish dose Pantethine is a way to achieve increased pregnenolone without taking the hormone directly.<\/p>\n Pantethine has powerful effects on blood lipids<\/a> as well. This works by increasing the availability of Co-Enzyme A<\/a> which then helps to significantly bring down cholesterol numbers<\/a>.<\/p>\n “A daily dose of 900mg has been shown to reduce triglyceride by up to 32% as well as a 19% drop in total cholesterol and a 21% drop in LDL ( the “bad” cholesterol) cholesterol . At the same time, HDL (the “good” cholesterol) rose by 23%. Pantethine also protects the heart and arteries and acts synergistically with vitamin E against cholesterol build up.” –\u00a0Dr. Lam<\/a><\/p>\nHyperlipidemia – High Cholesterol and Triglycerides<\/h4>\n