{"id":190,"date":"2015-08-26T18:00:05","date_gmt":"2015-08-26T18:00:05","guid":{"rendered":"http:\/\/www.surepaleo.com\/?p=190"},"modified":"2015-08-26T18:07:27","modified_gmt":"2015-08-26T18:07:27","slug":"pantethine-for-adrenal-dysfunction","status":"publish","type":"post","link":"http:\/\/www.surepaleo.com\/pantethine-for-adrenal-dysfunction\/","title":{"rendered":"Pantethine for Adrenal Dysfunction"},"content":{"rendered":"<p>I&#8217;ve struggled with adrenal dysfunction for quite some time and I&#8217;ve done tons of research on this. However, of all the recommendations out there for improving adrenal function this one is often left out or glossed over. If it&#8217;s mentioned, it rarely includes specific recommendations for dosing or much emphasis. I was grateful to finally learn this from Chris Kresser&#8217;s book as quoted below\u00a0and I quickly started supplementing. It&#8217;s helping already and I&#8217;m only on day 2 at the time of writing this.<\/p>\n<blockquote><p>\u201cPantethine, the active form of pantothenic acid (B5), is one of the most important nutrients for adrenal function. It is converted into an enzyme called co-enzyme A. Coenzyme A is required to produce adrenal hormones like cortisol and aldosterone, which support healthy adrenal function. The suggested dose of pantethine is 450 mg twice a day with food.\u201d \u2013 From Chris Kresser\u2019s Personal Paleo Code<\/p>\n<p>Co-enzyme A is ultimately converted to Acetyl Co-Enzyme A which has several functions in the body. It is produced by the krebs cycle and is part of the citric acid cycle. Therefore, it plays an important part in metabolism.<\/p>\n<p>Anyway, the important thing here is that CoA and cholesterol are used to produce pregnenolone which is the up-stream hormone that is converted into progesterone, then progesterone is converted into either aldosterone or cortisol.<\/p>\n<p>Taking more pregnenolone is often a treatment path for adrenal dysfunction, but taking high-ish dose Pantethine is a way to achieve increased pregnenolone without taking the hormone directly.<\/p>\n<p><a href=\"http:\/\/www.surepaleo.com\/vitamin-b5-pantethine-pantothenic-acid\/\">From Vitamin B5, Pantethine, Pantothenic Acid<\/a><\/p><\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>I&#8217;ve struggled with adrenal dysfunction for quite some time and I&#8217;ve done tons of research on this. However, of all the recommendations out there for improving adrenal function this one is often left out or glossed over. If it&#8217;s mentioned, it rarely includes specific recommendations for dosing or much emphasis. I was grateful to finally [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false}}},"categories":[1],"tags":[],"jetpack_publicize_connections":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Pantethine for Adrenal Dysfunction - Sure Paleo<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.surepaleo.com\/pantethine-for-adrenal-dysfunction\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pantethine for Adrenal Dysfunction - Sure Paleo\" \/>\n<meta property=\"og:description\" content=\"I&#8217;ve struggled with adrenal dysfunction for quite some time and I&#8217;ve done tons of research on this. 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